Osphena Side Effects

Osphena, oral prescription medication is used for the treatment of moderate to severe dyspareunia (pain during sexual intercourse), a symptom of vulvar and vaginal atrophy due to menopause. Dyspareunia is a condition associated with a declining level o hormone called estrogen during menopause.

Osphena works like estrogen in the lining of the uterus (womb) to make them less fragile resulting in pain reduction experienced during sexual intercourse. According to clinical trials, Osphena side effects do occur and may be mild to severe. You and your healthcare provider should talk regularly while taking Osphena medication. Osphena side effects include:

Side Effects of Osphena

Uterus Cancer or Vaginal Bleeding

Women taking Osphena medication are at higher risk of getting off the lining of the uterus (womb). The first warning sign and symptoms of uterus cancer include vaginal bleeding just after menopause. Tell your gynecologist right away if you are on Osphena medication and have vaginal bleeding, he/she may check any unusual bleeding to find out the root cause of the problem.

Cardiovascular Side Effects

Cardiovascular side effects are common and occur in 1 to 10 percent of patients treated with Osphena medication. The common Osphena side effect includes hot flashes, which occurred in 7.5 percent of the treated patients. The warning sign and symptoms of hot flashes include a feeling of warmth spreading through your upper body and face, a flushed appearance with red, blotchy skin, Rapid heartbeat, Perspiration, mostly on your upper body or a chilled feeling as the hot flash subsides.

Consult your doctor of hot flashes becomes bothersome and disrupts your daily routine. The uncommon cardiovascular side effects occurring in 0.1 to 1 percent of the Osphena treated patient may include Hemorrhagic stroke (results from a weakened vessel that ruptures and bleeds into the surrounding brain) and deep vein thrombosis ( formation of blood clot I deep veins particularly in legs).

The rare cardiovascular side effects occurring in 0.1 percent of the treated patients may include myocardial infarction or heart attack. See your healthcare provider right away if you have experienced any cardiovascular side effects while taking Osphena medication.
Excessive sweating

Women taking Osphena may have overactive sweat glands. Hyperhidrosis, a condition characterized by abnormally increased sweating is a common Osphena side effect reported in 0.1 percent of the treated patients. Although the symptoms are mild, it should be discussed with your health care provider.

Osphena Warnings

Osphena is not well tolerated by every patient. Women having a previous history of high blood pressure, high cholesterol (fat in the blood), and diabetes are at higher risk of getting heart disease using Osphena medication. Women using tobacco and are overweight are also more likely to get heart disease. Women having uterus should talk with their healthcare provider if Osphena is the right drug for them.

Osphena Overdose

As of 2013, there are no reported cases for Osphena overdose. Intake of higher than the recommended dosage of Osphena may cause symptoms such as hot flushes, genital discharge, muscle spasms, and excessive sweating. Talk with your doctor if you have taken a higher than the recommended dosage of Osphena.


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