Nesina Side Effects

Nesina, oral diabetes medication is used to control blood sugar levels by regulating the level of insulin your body produces after eating. Although the medication is well tolerated by patients, side effects do occur and may prove fatal.

Nesina’s side effects are usually minor and can be treated by you or your health care provider. But, in case of signs and symptoms of allergic reaction and liver problems, the patient should immediately seek medical attention. Side effect associated with Nesina medications include:

Side Effects of Nesina

Skin Reactions

People with Type 1 diabetes taking Nesina medication may experience mild to severe allergic reactions. As with any other medication, the Nesina side effect may also occur. The sign and symptoms of allergic reactions include unexplained rash, fever, sore throat, unexplained swelling on lips, face or tongue, burning sensation in your eyes, wheezing, difficulty breathing or swallowing and severe pain in the skin.

In some people, these symptoms are accompanied by a red or purple skin rash especially on the face and upper body. In a few people, Nesina’s medication may also cause peeling and blistering of the skin. Consult your health care provider in case of a mild reaction and seek medical attention for severe allergic reactions.


Headache is one of the most common side effects associated with Nesina. Clinical trials have reported headaches in 4.2 percent of Nesina treated patients. Headache may be severe (migraine) or mild. A person with headache may also experience pain in the mouth and neck. Headache is followed by a change in mood, irritability, and confusion. Few people may also experience sweating and dizziness. Talk to your healthcare provider before the discontinuation of the medication.


Pancreatitis, an inflammation of the pancreas is the most common side effect associated with Nesina. In clinical trials, Pancreatitis has been reported in 0.2 percent of the Nesina treated patients. Pancreatitis may cause signs and symptoms such as nausea and vomiting; swollen and tender abdomen; fever; and increased heart rate. Patients may also experience pain in the upper abdomen that may radiate into the back.

The side effects may get aggravated by eating food high in fat. Unfortunately, there is no way that your healthcare provider may know about your symptoms beforehand. So, it is advisable to consult your healthcare provider immediately in case of mild to severe side effects.


Hypoglycemia, low blood sugar is another severe Nesina side effect. The mediation itself does not cause side effects. However, hypoglycemia occurs when Nesina is taken in combination with another anti-diabetic medication. According to clinical trials, hypoglycemia occurred in 1.6 to 5.4 percent treated patients. Talk to your healthcare provider about all your diabetic medication before taking Nesina.

Signs and symptoms of low blood sugar include shakiness change in mood, such as irritability; sudden sweating, fast heartbeat, hunger, blurred vision, dizziness and tingling in hands and feet. Patients having hypoglycemia should carry sugar/glucose tablets to increase the level of blood sugar in the body.

In case you don’t have a tablet and you are experiencing any of the above symptoms then you can immediately take sugar candy, honey, or nondiet soda. Hypoglycemia mainly occurs due to the consumption of fewer calories, or unusually heavy exercise or consumption of alcohol. Eat your food regularly. Consult your doctor in case of severity.


Nesina side effects also include hyperglycemia or high blood sugar levels in the body. The sign and symptoms of high blood sugar levels include increased or frequent urination, drowsiness, flushing, confusion, rapid breathing, and fruity breath odor.

Talk to your talk if you experience such symptoms. The doctor might adjust your diabetes medication. It is advisable to check your blood sugar levels carefully at times of stress, travel, illness, surgery or medical emergency, and vigorous exercise.

Liver Problems

Nesina medication may also cause severe problems for your liver. People may experience fulminant hepatic failure, a disease characterized by the development of severe liver injury. Apart from that, the patient may also have elevation in liver enzymes.

The sign and symptoms of the liver problems include pain or swelling in the stomach; unexplained fatigue, dark colored urine and loss of appetite. Patients may also suffer from jaundice, a disease characterized by yellowing of the skin and whites of the eyes.

Consult your doctor if your skin has turned yellow or any of the above symptoms persists.

Nesina Overdose

As with any other medication, Nesina overdose may also cause severe side effects. The severity of side effects depends upon how much drug is taken or if it is taken in combination with another medication, drugs or alcohol.

Intake of higher than the recommended dosage of Nesina may cause a seizure (convulsions), extreme weakness, blurred vision, trouble speaking, sweating, tremors, severe abdominal pain, and confusion.

Inform your health care provider if you have taken a higher than the recommended dosage of Nesina medication or even if you have missed any dose of it.


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