Kynamro Side Effects

Kynamro drug, administered by subcutaneous injections is used to reduce the blood level of bad cholesterol from the body. As with any other medications, Kynamro’s side effects also occur. The recommended dosage of Kynamro is 200 mg once daily. Since the drug is not taken orally and is usually injected, the side effects associated with Kynamro overdosage seems unlikely. However, administration of higher than recommended dosage may prove fatal. Side effects associated with Kynamro injections include:

Side Effects of Kynamro

Liver fat

Kynamro injections may increase the level of liver fat (steatosis) in your body. Liver steatosis may, in turn, lead to advance live disease accompanied by steatohepatitis (inflammation of the liver with concurrent fat accumulation in the liver) and cirrhosis (a chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue, and regenerative nodules).

People administered with Kynamro medication should avoid the intake of alcohol as it may induce or exacerbate liver injury. Ask your doctor for complete liver testing before getting injected with Kynamro.

Injection Site Reaction

According to clinical trials, injection site reaction is the most common Kynamro side effect and is reported in 84 percent of the treated patients. The most common injection site reactions include pain at the site of injection, local swelling, erythema (redness of the skin), tenderness and pruritus (a sensation that causes a desire to scratch).

It is not necessary that the side effects occur with every injection. To minimize the side effects of injection site reaction it is important to follow the proper technique for subcutaneous administration.

Flu-like Symptoms

Clinical trials have reported that flu-like symptoms are associated with Kynamro injections. The symptoms have been reported in 30 percent of the treated patients. Flu symptoms associated with Kynamro medication include fever, chills, body aches, myalgia (muscle pain); pruritus (a sensation that causes the desire to scratch), arthralgia (pain in the joints) and fatigue. Such side effects may not occur after every injection and occur 2 days after the injection. Consult your doctor if you experience any of the above flu-like symptoms.

Allergic Reactions

Allergic reactions are very common side effects associated with Kynamro medication. In the initial phase of treatment, people have a mild rash. Some people may experience severe skin allergic reactions which are accompanied by itching or swelling on the face, tongue or throat; fever, difficulty in swallowing or breathing; and hives.

Some people may also experience painful skin rash on the face and upper part of the body. These painful rashes are usually of a reddish color and may cause flaking or peeling of the skin. The symptoms can be reversed by the discontinuation of Kynamro medication. Call your health care provider immediately in case of severe allergic reactions.

Other Liver Problem

Kynamro medication may also cause severe problems for your liver. The sign and symptoms of the liver problems include pain or swelling in the stomach; unusual and unexplained fatigue, dark colored urine and loss of appetite. Patients may also suffer from jaundice, a disease characterized by yellowing of the skin and whites of the eyes. Consult your doctor if your skin has turned yellow or any of the above symptoms persists.


Kynamro injections should not be injected into the skin areas that are swollen, sunburned or affected by a condition such as skin rash. People drinking alcohol are the greater risk of having liver damage. People taking Kynamro should avoid eating food that is high in cholesterol or fat. Kynamro drug will not be effective in injected along with the intake of food high in cholesterol.


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